Literature summary extracted from

Knopf, J.D.; Tholen, S.; Koczorowska, M.M.; De Wever, O.; Biniossek, M.L.; Schilling, O.
The stromal cell-surface protease fibroblast activation protein-alpha localizes to lipid rafts and is recruited to invadopodia (2015), Biochim. Biophys. Acta, 1853, 2515-2525 .

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.4.21.B28	cell surface	-	Homo sapiens	9986	-
3.4.21.B28	invadopodium	-	Homo sapiens	71437	-
3.4.21.B28	plasma membrane	-	Homo sapiens	5886	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.B28	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.B28	fibroblast	expressed by cancer-associated fibroblasts in the microenvironment of most solid tumors	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.B28	FAPalpha	-	Homo sapiens
3.4.21.B28	fibroblast activation protein-alpha	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
3.4.21.B28	physiological function	the enzyme may contributes to the focal matrix-degrading capability of stromal invadopodia	Homo sapiens

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Release 2023.1 (January 2023)